Wednesday


Orphenadrine citrate

Brand names Biorphen, Disipal, Norflex .

Used in the following combined preparations
None


Orphenadrine is an anticholinergic drug that is prescribed to treat all forms of Parkinson'sdisease. Although it is less effective than other drugs used in the treatment of this disorder, it is often preferred because its adverse effects tend to be less severe. Orphenadrine is particularly valuable for relieving the muscle rigidity that often occurs with Parkinson's disease; it is less helpful for improving slowing of movement that also commonly affects sufferers.

Effervescent Tablets-Kamagra Effervescent


Orphenadrine possesses significant muscle-relaxant properties. It produces this effect by blocking nerve pathways responsible for muscle rigidity and spasm. Consequently, it is prescribed for the relief of muscle spasm caused by muscle injury, prolapsed ("slipped") disc, and whiplash injuries.



Tablets, liquid, injection.
2-3 x daily.
150-400mg daily.
Within 60 minutes (by mouth); within 5 minutes (by injection).
8-12 hours.
None.
Keep in a closed container in a cool, dry place out of the reach of children. Protect from light.
Take as soon as you remember. If your next dose is due within 2 hours, take a single dose now and skip the next.
Do not stop the drug without consulting your doctor; symptoms may recur.


Seek immediate medical advice in all cases. Take emergency action if palpitations, fits, or loss of consciousness occur.

The adverse effects of orphenadrine are similar to those of other anticholinergic drugs. The more common symptoms,
such as dryness of the mouth and blurred vision, can often be overcome by an adjustment in dosage.


Symptom/effect
Frequency
Common
Rare
Discus; doctor
Only if severe
with
In all
cases
Stop taking drug now
Call
doctor
now
Dry mouth/skin




Difficulty passing urine




Constipation




Dizziness




Blurred vision




Confusion/agitation




Rash/itching



Palpitations


1


interactions
Anticholinergic drugs The anticholinergic effects of orphenadrine are likely to be increased by these drugs.
Confusion, anxiety, and tremors may occur if these drugs are taken with orphenadrine.
Sedatives The effects of all drugs that have a sedative effect on the central nervous system are likely to be increased with orphenadrine.


Drug group Anticholinergic muscle relaxant and drug for parkinsonism .

Overdose danger rating High
Dependence rating Low
Prescription needed Yes
Available as generic Yes


      You have long-term liver or kidney problems.
      You have heart problems.
      You have had glaucoma.
      You have difficulty passing urine.
      You have myasthenia gravis.
  You are taking other medications.
       Safety in pregnancy not established. Discuss with your doctor.
       The drug passes into the breast milk, but at normal doses adverse effects on the baby are unlikely. Discuss with your doctor.
       Not usually prescribed.
     Increased likelihood of adverse effects. Reduced dose may therefore be necessary.
     Avoid such activities until you have learned how orphenadrine affects you because the drug can cause dizziness, lightheadedness, and blurred vision.
  Avoid. Alcohol may increase the sedative effects of this drug.

No problems expected. Effectiveness in treating Parkinson's disease may diminish with time.

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